• Automated segmentation of magnetic resonance bone marrow signal: a feasibility study 

      von Brandis, Elisabeth; Jenssen, Håvard Bjørke; Avenarius, Derk Frederik Matthaus; Bjørnerud, Atle; Flatø, Berit; Tomterstad, Anders; Lilleby, Vibke; Rosendahl, Karen; Sakinis, Tomas; Zadig, Pia Karin Karlsen; Müller, Lil-Sofie Ording (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-02)
      Background - Manual assessment of bone marrow signal is time-consuming and requires meticulous standardisation to secure adequate precision of findings.<p> <p>Objective - We examined the feasibility of using deep learning for automated segmentation of bone marrow signal in children and adolescents.<p> <p>Materials and methods - We selected knee images from 95 whole-body MRI examinations of ...
    • Chronic nonbacterial osteomyelitis — clinical and magnetic resonance imaging features 

      d’Angelo, Paola; de Horatio, Laura Tanturri; Toma, Paolo; Ording Müller, Lil-Sofie; Avenarius, Derk; von Brandis, Elisabeth; Zadig, Pia; Casazza, Ines; Pardeo, Manuela; Pires-Marafon, Denise; Capponi, Martina; Insalaco, Antonella; Fabrizio, Benedetti; Rosendahl, Karen (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-09)
      <i>Background</i> - Chronic nonbacterial osteomyelitis (CNO) is a rare autoinflammatory bone disorder. Little information exists on the use of imaging techniques in CNO.<p> <p><i>Materials and methods</i> - We retrospectively reviewed clinical and MRI findings in children diagnosed with CNO between 2012 and 2018. Criteria for CNO included unifocal or multifocal inflammatory bone lesions, symptom ...
    • COL11A1 is associated with developmental dysplasia of the hip and secondary osteoarthritis in the HUNT study 

      Jacobsen, Kaya Kvarme; Børte, Sigrid; Laborie, Lene Bjerke; Kristiansen, Hege; Schäfer, Annette; Gundersen, Trude; Zayats, Tetyana; Winsvold, Bendik Kristoffer Slagsvold; Martinsen, Amy; Skogholt, Anne Heidi; Brumpton, Ben Michael; Willer, Cristen J; Fors, Egil Andreas; Kristoffersen, Espen Saxhaug; Heuch, Ingrid; Mundal, Ingunn Pernille; Zwart, John Anker Henrik; Nielsen, Jonas B.; Storheim, Kjersti; Hagen, Knut; Nilsen, Kristian Bernhard; Hveem, Kristian; Fritsche, Lars G; Thomas, Laurent Francois; Pedersen, Linda Margareth; Gabrielsen, Maiken Elvestad; Lie, Marie U.; Stensland, Synne; Zhou, Wei; Rosendahl, Karen (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-16)
      Objective: Developmental dysplasia of the hip (DDH) is a congenital condition affecting 2-3% of all infants. DDH increases the risk of osteoarthritis, is the cause of 30% of all total hip arthroplasties (THAs) in adults <40 years of age and can result in loss of life quality. Our aim was to explore the genetic background of DDH in order to improve diagnosis, management and longterm outcome.<p><p> ...
    • Cone beam computed tomography in the assessment of TMJ deformity in children with JIA: repeatability of a novel scoring system 

      Angenete, Oskar W; Augdal, Thomas Angell; Shi, Xie-Qi; Säll, Mats; Fischer, Johannes Maria; Nordal, Ellen Berit; Rosendahl, Karen (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-10)
      Background The temporomandibular joint (TMJ) is frequently involved in juvenile idiopathic arthritis (JIA). Diag‑ nostic imaging is necessary to correctly diagnose and evaluate TMJ involvement, however, hitherto little has been published on the accuracy of the applied scoring systems and measurements. The present study aims to investigate the precision of 20 imaging features and fve measurements ...
    • Dental caries in children and adolescents with juvenile idiopathic arthritis and controls: a multilevel analysis 

      Gil, Elisabeth G.; Åstrøm, Anne-Kristine N; Lie, Stein Atle; Rygg, Marite; Fischer, Johannes; Rosén, Annika; Bletsa, Athanasia; Luukko, Keijo; Shi, Xie-Qi; Halbig, Josefine; Frid, Paula; Cetrelli, Lena Elisabet; Tylleskär, Karin; Rosendahl, Karen; Skeie, Marit Slåttelid (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-25)
      Background - Optimal utilization of dental caries data is crucial in epidemiological research of individuals with juvenile idiopathic arthritis (JIA). The aims were to: explore whether caries is more prevalent among children and adolescents with JIA compared to controls; examine presence of caries according to JIA group, socio-behavioral and intraoral characteristics, and the extent to which ...
    • Dental plaque and gingival bleeding in adolescents with juvenile idiopathic arthritis and controls: a multilevel analysis 

      Gil, Elisabeth Grut; Åstrøm, Anne-Kristine N; Lie, Stein Atle; Rygg, Marite; Fischer, Johannes; Rosén, Annika; Bletsa, Athanasia; Luukko, Keijo Aukusti; Shi, Xie-Qi; Halbig, Josefine Mareile; Frid, Paula Hanna Therese; Cetrelli, Lena Elisabet; Tylleskär, Karin; Rosendahl, Karen; Skeie, Marit Slåttelid (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-30)
      Objective - To explore whether plaque and gingival bleeding are more frequently experienced by adolescents with juvenile idiopathic arthritis (JIA) compared to matched controls without JIA; explore whether surface- and site-specific periodontal outcomes vary between the two groups; and for participants with JIA, investigate associations between disease-specific features and periodontal outcomes.<p ...
    • The effect of selective ultrasound screening on the incidence of late presentation of developmental hip dysplasia—a meta-analysis 

      Laborie, Lene Bjerke; Rosendahl, Karen; Dhouib, Amira; Simoni, Paolo; Tomà, Paolo; Offiah, Amaka C (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-04-26)
      Different screening strategies for developmental dysplasia of the hip (DDH) exist. Despite screening efforts, cases of late presentation continue to occur, often necessitating surgery. This systematic review and meta-analysis assess the effect of newborn selective ultrasound screening for DDH on the incidence of late presentation in infants and children, compared to a universal ultrasound strategy. ...
    • Effects of motion correction, sampling rate and parametric modelling in dynamic contrast enhanced MRI of the temporomandibular joint in children affected with juvenile idiopathic arthritis 

      Starck, Lea; Andersen, Erling; Macíček, Ondřej; Angenete, Oskar W; Augdal, Thomas Angell; Rosendahl, Karen; Jirík, Radovan; Grüner, Renate (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-13)
      The temporomandibular joint (TMJ) is typically involved in 45–87% of children with Juvenile Idiopathic Arthritis (JIA). Accurate diagnosis of JIA is difficult as various clinical tests, including MRI, disagree. The purpose of this study is to optimize the methodological aspects of Dynamic Contrast Enhanced (DCE) MRI of the TMJ in children. In this cross-sectional study, including data from 73 JIA ...
    • Efficacy and safety of intraarticular corticosteroid injections in adolescents with juvenile idiopathic arthritis in the temporomandibular joint: A Norwegian 2-year prospective multicenter pilot study 

      Frid, Paula; Augdal, Thomas Angell; Larheim, Tore Arne; Halbig, Josefine Mareile; Rypdal, Veronika Gjertsen; Songstad, Nils Thomas; Rosén, Annika; Tylleskär, Karin; Berstad, Johanna Elisabeth Rykke; Flatø, Berit; Stoustrup, Peter; Rosendahl, Karen; Kirkhus, Eva Astrid; Nordal, Ellen Berit (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-01)
      <p><i>Background - </i>Intraarticular corticosteroids (IACs) have been used to treat temporomandibular joint (TMJ) arthritis. However, prospective clinical studies with magnetic resonance imaging (MRI) scoring are lacking. The aim of this study was to examine efficacy and safety of a single IAC in the TMJ in adolescents with juvenile idiopathic arthritis (JIA) in a clinical setting. <p><i>Methods ...
    • Erosion or normal variant? 4-year MRI follow-up of the wrists in healthy children 

      Avenarius, Derk; Müller, Lil-Sofie Ording; Rosendahl, Karen (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-12-04)
      Background A large proportion of healthy children have wrist changes on MRI, namely carpal depressions, findings that have been described as pathological in children with juvenile idiopathic arthritis.<p> <p>Objective We performed follow-up imaging in a cohort of healthy children to evaluate carpal surface depressions over time, focusing on the presence of overlying cartilage as a potential ...
    • European recommendations on practices in pediatric neuroradiology: consensus document from the European Society of Neuroradiology (ESNR), European Society of Paediatric Radiology (ESPR) and European Union of Medical Specialists Division of Neuroradiology (UEMS) 

      Rossi, Andrea; Argyropoulou, Maria; Zlatareva, Dora; Boulouis, Gregoire; Pizzini, Francesca B.; van den Hauwe, Luc; Raissaki, Maria; Pruvo, Jean-Pierre; Rosendahl, Karen; Hoffmann, Chen; Sundgren, Pia C.; Mankad, Kshitij; Severino, Mariasavina; Adamsbaum, Catherine; Altmann-Schneider, Irmhild; Chateil, Jean-François; Connolly, Daniel J.; Dangouloff-Ros, Volodia; D’Arco, Felice; Donoghue, Veronica; Girard, Nadine; Krystal, Sidney; Lequin, Maarten Hans; Narayana, Dhananjaya; Porto, Luciana; Vasquez, Elida; Xydis, Vasileios (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-05)
      Pediatric neuroradiology is a subspecialty within radiology, with possible pathways to train within the discipline from neuroradiology or pediatric radiology. Formalized pediatric neuroradiology training programs are not available in most European countries. We aimed to construct a European consensus document providing recommendations for the safe practice of pediatric neuroradiology. We particularly ...
    • Hofteleddsdysplasi hos spedbarn – screening, behandling og oppfølging 

      Laborie, Lene Bjerke; Klingenberg, Claus Andreas; Rasmussen, Hanne; Gundersen, Trude; Rosendahl, Karen (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-04-19)
      Hofteleddsdysplasi forkommer hos opptil 3 % av nyfødte og kan ubehandlet føre til luksert hofteledd, osteoartritt og behov for hofteprotese. Målet med studien var å kartlegge rutiner for ultralydscreening, behandling og oppfølging av hofteleddsdysplasi ved norske sykehus.
    • Hormone references for ultrasound breast staging and endocrine profiling to detect female onset of puberty 

      Madsen, Andre; Bruserud, Ingvild Særvold; Bertelsen, Bjørn-Erik; Roelants, Mathieu; Oehme, Ninnie; Viste, Kristin; Bjerknes, Robert; Almås, Bjørg; Rosendahl, Karen; Mellgren, Gunnar; Sagen, Jørn V.; Juliusson, Petur Benedikt (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-22)
      <p><i>Context - </i>Application of ultrasound (US) to evaluate attainment and morphology of glandular tissue provides a new rationale for evaluating onset and progression of female puberty, but currently no hormone references complement this method. Furthermore, previous studies have not explored the predictive value of endocrine profiling to determine female puberty onset. <p><i>Objective - </i>To ...
    • Human blood serum proteome changes after 6 hours of sleep deprivation at night 

      Bjørkum, Alvhild Alette; Duran, Ana Carasco; Roy, Dola Sinha; Rosendahl, Karen; Birkeland, Even; Stuhr, Linda Elin Birkhaug (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-25)
      Background: The aim of this study was to discover significantly changed proteins in human blood serum after loss of 6 h sleep at night. Furthermore, to reveal affected biological process- and molecular function categories that might be clinically relevant, by exploring systems biological databases.<p> <p>Methods: Eight females were recruited by volunteer request. Peripheral venous whole blood was ...
    • In children and adolescents with temporomandibular disorder assembled with juvenile idiopathic arthritis ‑ no association were found between pain and TMJ deformities using CBCT 

      Fischer, Johannes Maria; Augdal, Thomas Angell; Angenete, Oskar W; Gil, Elisabeth Grut; Skeie, Marit Slåttelid; Åstrøm, Anne-Kristine N; Tylleskär, Karin; Rosendahl, Karen; Shi, Xie-Qi (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-12)
      Background - Children and adolescents with juvenile idiopathic arthritis (JIA) may suffer from temporomandibular disorder (TMD). Due to this, imaging diagnosis is crucial in JIA with non-symptomatic TM joint (TMJ) involvement. The aim of the study was to examine the association between clinical TMD signs/symptoms and cone-beam computed tomography (CBCT) findings of TMJ structural deformities in ...
    • Incidence, pattern and mechanisms of injuries and fractures in children under two years of age 

      Rosendahl, Karen; Myklebust, Ramona; Ulriksen, Kjersti Foros; Nøttveit, Andreas; Eide, Pernille; Djuve, Åsmund; Brudvik, Christina Elisabeth (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-18)
      Background - Fractures in children under 2 years of age are rare, and little has been published on their mechanisms. We aimed at examining the incidence, mechanisms, pattern and fracture characteristics in a large, population-based cohort of otherwise healthy children.<p> <p>Methods - This retrospective, cross-sectional study includes all children aged 0–2 years, attending the Accident and Emergency ...
    • Low BMI, but not high BMI, influences the timing of puberty in boys 

      Oehme, Ninnie Helen Bakken; Roelants, Mathieu; Bruserud, Ingvild Særvold; Madsen, Andre; Bjerknes, Robert; Rosendahl, Karen; Juliusson, Pétur Benedikt (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-05)
      Background - Previous studies investigating the association between weight status and onset of puberty in boys have been equivocal. It is currently unclear to what extent weight class influences puberty onset and progression.<p> <p>Objectives - To explore the relationship between degree of sexual maturation and anthropometric measures in Norwegian boys.<p> <p>Methods - The following endpoints ...
    • Management strategies for children with COVID-19: ESPR practical recommendations 

      Raissaki, Maria; Shelmerdine, Susan; Damasio, Beatrice; Toso, Seema; Kvist, Ola; Lovrenski, Jovan; Hirsch, Franz Wolfgang; Görkem, Süreyya Burcu; Paterson, Anne; Arthurs, Owen J.; Rossi, Andrea; van Schuppen, Joost; Petit, Philippe; Argyropoulou, Maria I.; Offiah, Amaka C.; Rosendahl, Karen; Caro-Domínguez, Pablo (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-03)
      During the outbreak of the COVID-19 pandemic, guidelines have been issued by international, national and local authorities to address management and the need for preparedness. Children with COVID-19 differ from adults in that they are less often and less severely affected. Additional precautions required in the management of children address their increased radiosensitivity, need for accompanying ...
    • MRI in the Assessment of TMJ-Arthritis in Children with JIA; Repeatability of a Newly Devised Scoring System 

      Angenete, Oskar W; Augdal, Thomas Angell; Rygg, Marite; Rosendahl, Karen (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-19)
      Rationale and Objectives: The temporomandibular joint (TMJ) is commonly involved in children with juvenile idiopathic arthritis. The diagnosis and evaluation of the disease progression is dependent on medical imaging. The precision of this imaging is under debate. SeveralR scoring systems have been proposed but transparent testing of the precision of the constituents of the scoring systems is ...
    • Non-radiologist-performed abdominal point-of-care ultrasonography in paediatrics — a scoping review 

      van Wassenaer, Elsa A.; Daams, Joost G.; Benninga, Marc A.; Rosendahl, Karen; Koot, Bart G.P.; Stafrace, Samuel; Arthurs, Owen J.; van Rijn, Rick R. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-10)
      <i>Background</i> - Historically, US in the paediatric setting has mostly been the domain of radiologists. However, in the last decade, there has been an uptake of non-radiologist point-of-care US.<br><br> <i>Objective</i> - To gain an overview of abdominal non-radiologist point-of-care US in paediatrics.<br><br> <i>Materials and methods</i> - We conducted a scoping review regarding the uses ...